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2021 GMC Sierra 2500HD Overview, Reviews, Ratings & Specs

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Eugene S | March 31, 2025
The 2021 GMC Sierra 2500HD is a heavy-duty pickup truck designed for demanding tasks. It's part of the fourth generation of Sierra HD models. Available as a regular cab, double cab, or crew cab, it offers several trims including base, SLE, SLT, AT4, and Denali. Pricing ranges from approximately $36,000 to $70,000+, depending on configuration and options. Its bold styling and available technology, like the MultiPro tailgate, make it popular for both work and recreation.
The Good

The 2021 GMC Sierra 2500HD boasts powerful engine options for serious towing and hauling. Its refined interior offers comfort for long drives. The bold design makes a statement, while its reputation for reliability provides peace of mind. For practical buyers, its capability is unmatched; emotional buyers appreciate its premium feel and distinctive look.

The Bad

The 2021 GMC Sierra 2500HD's ride quality can be stiff, especially when unladen. Some find the interior materials lacking compared to rivals, particularly in lower trims. Fuel economy is poor, as expected for a heavy-duty truck. Watch for potential issues with the infotainment system and certain diesel engine components. Overall size can make it difficult to maneuver in tight spaces.

2021 GMC Sierra 2500HD: Quick Overview

Here's a summary of the 2021 GMC Sierra 2500HD's key specifications:

  • Engine Options:
    • 6.6L V8 Gas: 401 hp, 464 lb-ft of torque
    • 6.6L Duramax Turbo-Diesel V8: 445 hp, 910 lb-ft of torque
  • Horsepower: 401 hp (Gas), 445 hp (Diesel)
  • Fuel Economy: Fuel economy is not officially rated for heavy-duty trucks by the EPA. Expect significantly lower MPG than light-duty trucks, especially when towing. Real-world MPG varies greatly.
  • 0-60 Times: Not a primary focus for heavy-duty trucks, but expect roughly 7-8 seconds for the gas engine and slightly quicker for the diesel.
  • Towing Capacity: Up to 18,510 lbs (Gas), Up to 18,500 lbs (Diesel). These figures depend on configuration.
  • Trim-Level Features:
    • Base: Vinyl seats, basic infotainment system, work truck essentials.
    • SLE: Cloth seats, upgraded infotainment, chrome exterior trim.
    • SLT: Leather seats, premium infotainment, dual-zone climate control.
    • AT4: Off-road focused, with Rancho shocks, skid plates, and unique styling.
    • Denali: Top-of-the-line, with premium leather, wood trim, advanced technology, and unique Denali styling.

2021 GMC Sierra 2500HD Specifications

Vehicle Information
Year 2021
Make GMC
Model Sierra 2500HD
Trim -
Style Double Cab 4WD
Type Truck
Category Standard Pickup Truck
Manufacturing Details
Made In United States
Manufacturing City FLINT
Dimensions
Doors 4-Door
Curb Weight 3055.4 kg
Gross Vehicle Weight Rating 6350.29 kg
Overall Height 203.2 cm
Overall Length 610.87 cm
Overall Width 208.03 cm
Wheelbase Length 379.48 cm
Standard Seating 6
Engine & Performance
Engine 6.6-L V-8
Engine Size 6.6L
Engine Cylinders 8
Transmission Automatic
Transmission Type Automatic
Transmission Speeds -
Drivetrain Four-Wheel Drive
Additional Features
Anti-Brake System 4-Wheel ABS
Steering Type Recirculating
Pricing
Manufacturer Suggested Retail Price (MSRP) $42,895 USD
Invoice Price $40,665 USD
Delivery Charges $1,595 USD

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What Problems Does the 2021 GMC Sierra 2500HD Have?

The 2021 GMC Sierra 2500HD has had some reported problems. Some owners have reported issues with the infotainment system, including glitches, freezing, and unresponsive touchscreens. There have also been reports related to the diesel engine, specifically concerning the fuel injection system and emissions components. Some owners have experienced issues with the diesel exhaust fluid (DEF) system and related sensors. It's important to check for any active recalls related to the vehicle's VIN.

Long-term reliability concerns often revolve around the complexity of modern diesel engines and their associated emissions controls. Regular maintenance, including oil changes and fuel filter replacements, is crucial for longevity. Some model years of the Sierra HD have had recalls related to brake system issues, airbag deployment, and fuel system components. Prospective buyers should research the specific VIN of any vehicle they are considering to determine if any recalls apply. It's also advisable to review owner forums and reliability reports for a more comprehensive understanding of potential issues.

How long will the 2021 GMC Sierra 2500HD last?

With proper maintenance, the 2021 GMC Sierra 2500HD can easily exceed 200,000 miles or 10-15 years of service. Diesel engines, in particular, are known for their longevity when well-maintained. However, long-term durability hinges on consistent maintenance habits. Weaknesses may emerge in the electrical system, particularly with the infotainment screen and sensors. Rust can also be a concern in regions with harsh winters. Regular undercarriage washing and rustproofing can mitigate this. Suspension components, especially ball joints and tie rod ends, may require replacement over time, particularly if the truck is frequently used for heavy towing.

What Technology & Safety Features are Included?

The 2021 GMC Sierra 2500HD comes standard with a user-friendly infotainment system, including Apple CarPlay and Android Auto compatibility. Higher trims offer larger touchscreens, premium audio systems (like Bose), and built-in navigation. Available driver-assistance features include forward collision alert, lane departure warning, automatic emergency braking, and blind-spot monitoring. Adaptive cruise control is also available as an option.

Safety features include multiple airbags, electronic stability control, and traction control. The Sierra 2500HD also offers a high-definition surround vision camera system, which is incredibly useful for maneuvering in tight spaces and when hooking up a trailer. The MultiPro tailgate is another innovative feature, offering multiple configurations for easier bed access and loading. As for crash-test ratings, the NHTSA and IIHS ratings can vary. While complete overall scores may not always be available for heavy-duty trucks, individual tests on certain aspects are often conducted. Check official sources for the most up-to-date crash test information.

What Colors Options are Available?

Exterior Colors
Summit White
Onyx Black
Pacific Blue Metallic
Cardinal Red
Dark Sky Metallic
Hunter Metallic
Quicksilver Metallic
Brownstone Metallic
Interior Colors
Cocoa/Dark Sand
Jet Black

2021 GMC Sierra 2500HD Prices and Market Value

The 2021 GMC Sierra 2500HD had a starting MSRP around $36,000, with higher trims like the Denali exceeding $70,000 when new. Current used market prices vary depending on mileage, condition, and trim, but expect to see prices ranging from $38,000 to $65,000+. Depreciation is moderate for heavy-duty trucks, especially those with diesel engines, as they retain their value well. Factors affecting resale value include engine type (diesel models hold value better), trim level (Denali and AT4 trims are desirable), overall condition, maintenance history, and mileage. A clean title and documented service records significantly boost resale value.

2021 GMC Sierra 2500HD Cost of Ownership

The 2021 GMC Sierra 2500HD is generally considered costly to own. Insurance premiums are higher due to the vehicle's size and potential repair costs. Fuel costs are substantial, particularly with the diesel engine and frequent towing. Maintenance, including oil changes and tire replacements, is more expensive than for light-duty vehicles. Repairs can also be costly, especially those involving the diesel engine or complex electronics. While durable, long-term ownership requires a significant financial commitment.

2021 GMC Sierra 2500HD Fuel Efficiency

Fuel Type Diesel
Fuel Capacity 136.27 liters
City Mileage -
Highway Mileage -

2021 GMC Sierra 2500HD Warranty

Basic
Original warranty 36 months / 36,000 miles
Estimated remaining Expired
Powertrain
Original warranty 60 months / 60,000 miles
Estimated remaining 12 months / 60,000 miles
Rust
Original warranty 72 months / 100,000 miles
Estimated remaining 24 months / 100,000 miles

2021 GMC Sierra 2500HD Insurance

Insurance for a 2021 GMC Sierra 2500HD is moderately priced, reflecting its status as a Truck with strong safety ratings and
reasonable repair costs.

How Does the 2021 GMC Sierra 2500HD Compare to Other Truck?

The 2021 GMC Sierra 2500HD competes directly with the Ford Super Duty (F-250/F-350) and the Ram 2500/3500. In terms of performance, all three offer comparable power and towing capabilities. The Ford Super Duty boasts strong engine options and a robust frame. The Ram 2500/3500 is often praised for its comfortable ride quality, especially with the available rear air suspension. The Sierra 2500HD distinguishes itself with its upscale Denali trim and available MultiPro tailgate.

Feature-wise, all three trucks offer similar technology and driver-assistance features, though specific availability may vary by trim. Reliability is a mixed bag across all brands, with each having its own set of potential issues. Price points are also comparable, with variations depending on configuration and options. If ride comfort is a top priority, the Ram 2500 might be a better choice. If you prioritize cutting-edge technology and unique features like the MultiPro tailgate, the Sierra 2500HD is a strong contender. The Ford Super Duty is a solid all-around performer with a strong reputation for durability. Ultimately, the best choice depends on individual needs and preferences.

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Final Verdict: Is the 2021 GMC Sierra 2500HD a Good Truck?

The 2021 GMC Sierra 2500HD is ideal for individuals and businesses needing a capable and refined heavy-duty truck for towing and hauling. Whether it's worth buying depends on budget and needs. A used 2021 model can offer significant savings compared to new. Consider the SLT, AT4, or Denali trims for a better blend of features and comfort. If budget is a concern, a well-maintained SLE can be a good value. Ensure a thorough inspection and review the vehicle's history before purchasing, paying close attention to any potential diesel engine issues. If heavy towing is a frequent need, the diesel engine is preferable, but for lighter duties, the gas engine is sufficient.

2021 GMC Sierra 2500HD Owner Reviews

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Eugene S

Eugene is an automotive enthusiast with over 15 years of experience in the used car market. As a writer at VINCheck.info, he brings deep industry insight and a passion for cars, helping readers make smart, informed decisions. Eugene has written hundreds of used car reviews and is known for breaking down complex automotive topics into clear, actionable advice. Over the years, he has driven and worked on a wide range of vehiclesβ€”starting with tuning street cars in his early days and eventually focusing on performance upgrades and reliability improvements. Today, he specializes in evaluating used vehicles through the lens of real-world ownership and enthusiast needs. A longtime fan of Porsche, Eugene especially appreciates vehicles that blend durability with driving enjoyment.