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2021 Mercedes-Benz CLS-Class Overview, Reviews, Ratings & Specs

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Drew B | March 31, 2025
The Mercedes-Benz CLS-Class, a pioneer of the "four-door coupe" design, continues its legacy with the 2021 model. This sleek sedan blends coupe-like styling with the practicality of four doors. Key trims include the CLS 450. The CLS-Class stands out due to its elegant design, luxurious interior, and advanced technology. Pricing generally ranges from $70,000 to $85,000, depending on options and trim level.
The Good

The 2021 CLS-Class offers a compelling blend of performance and luxury. It boasts strong engine performance and a comfortable ride. The sleek design appeals to the emotional buyer, while the spacious interior and fuel efficiency satisfy practical needs. Overall, it is reliable and a joy to drive.

The Bad

Potential weaknesses of the 2021 CLS-Class include a relatively firm ride on rough roads, especially with larger wheel options. The rear headroom can be limited due to the sloping roofline. Some owners have reported issues with the infotainment system. Maintenance costs can be high, as is typical for luxury vehicles.

2021 Mercedes-Benz CLS-Class: Quick Overview

  • Engine Options: The 2021 CLS-Class primarily features a 3.0-liter inline-6 turbocharged engine with mild hybrid assist.

  • Horsepower: The CLS 450 delivers 362 horsepower and 369 lb-ft of torque. The AMG CLS 53 boosts this to 429 horsepower and 384 lb-ft of torque.

  • Fuel Economy: The CLS 450 achieves an EPA-estimated fuel economy of around 22 mpg city and 30 mpg highway.

  • 0-60 Times: The CLS 450 accelerates from 0 to 60 mph in approximately 4.8 seconds. The AMG CLS 53 shaves this down to around 4.4 seconds.

  • Towing Capacity: The CLS-Class is not designed for towing; therefore, it has no significant towing capacity.

  • Trim-Level Features (CLS 450):
    • Standard features include a 12.3-inch infotainment display, a 12.3-inch digital instrument cluster, leather upholstery, heated front seats, sunroof, ambient lighting, Apple CarPlay, and Android Auto.
    • Advanced safety features include automatic emergency braking, blind-spot monitoring, and lane-keeping assist.
    • Optional features include air suspension, upgraded audio systems (Burmester), massaging front seats, a head-up display, and adaptive cruise control.
  • Trim-Level Features (AMG CLS 53):
    • Includes all features of the CLS 450, plus AMG-specific styling elements, an AMG performance exhaust, AMG Ride Control+ air suspension, and enhanced brakes.
    • AMG models also feature unique interior trim and performance-oriented displays.

2021 Mercedes-Benz CLS-Class Specifications

Vehicle Information
Year 2021
Make Mercedes-Benz
Model CLS-Class
Trim -
Style Coupe
Type Coupe
Category Minicompact Car
Manufacturing Details
Made In Germany
Manufacturing City SINDELFINGEN
Dimensions
Doors 4-Door
Curb Weight -
Gross Vehicle Weight Rating -
Overall Height -
Overall Length -
Overall Width -
Wheelbase Length -
Standard Seating 5
Engine & Performance
Engine M256
Engine Size 3L
Engine Cylinders 6
Transmission 9-Speed Automatic
Transmission Type Automatic
Transmission Speeds 9-Speed
Drivetrain All-Wheel Drive
Additional Features
Anti-Brake System Standard
Steering Type -
Pricing
Manufacturer Suggested Retail Price (MSRP) -
Invoice Price -
Delivery Charges -

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Analysis

What Problems Does the 2021 Mercedes-Benz CLS-Class Have?

While the 2021 Mercedes-Benz CLS-Class is generally considered reliable, some frequently reported problems and potential long-term reliability concerns should be noted. Some owners have reported issues with the MBUX infotainment system, including software glitches, connectivity problems, and slow response times. Electrical issues, such as malfunctioning sensors or problems with the auxiliary battery, have also been reported, though not widespread. Air suspension, if equipped, can be a potential source of problems as the car ages, leading to expensive repairs.

Recalls for the 2021 CLS-Class have been issued for issues such as improperly installed seat belts, potential fuel leaks, and malfunctioning airbags. It's essential to check the vehicle's VIN with the NHTSA database to determine if any recalls apply.

Long-term reliability hinges on proper maintenance and adherence to the recommended service schedule. Neglecting scheduled maintenance, especially oil changes and fluid flushes, can accelerate wear and tear on critical components. Pre-purchase inspections by a qualified mechanic are highly recommended, especially for used models, to identify any potential problems before purchase.

How long will the 2021 Mercedes-Benz CLS-Class last?

With regular maintenance, the 2021 Mercedes-Benz CLS-Class can easily achieve 150,000 to 200,000 miles or 10-15 years of service. Proper maintenance habits, including timely oil changes, fluid flushes, and addressing minor issues promptly, are crucial for longevity. Long-term durability can be affected by factors such as climate, driving conditions, and the quality of replacement parts used during repairs. Weaknesses may include potential issues with the air suspension (if equipped) and the infotainment system over time. The electrical system may also exhibit minor quirks as the vehicle ages.

What Technology & Safety Features are Included?

The 2021 Mercedes-Benz CLS-Class boasts a comprehensive suite of technology, entertainment, driver-assistance, and safety features. The MBUX infotainment system, featuring a 12.3-inch touchscreen and a 12.3-inch digital instrument cluster, provides intuitive control over vehicle functions, navigation, and entertainment. Standard entertainment features include Apple CarPlay, Android Auto, and a premium audio system.

Driver-assistance features include standard automatic emergency braking, blind-spot monitoring, lane-keeping assist, and a rearview camera. Optional driver-assistance features include adaptive cruise control, lane change assist, and a 360-degree camera system. These systems enhance safety and convenience during everyday driving.

Safety features encompass a robust suite of airbags, stability control, and anti-lock brakes. While official crash-test ratings from the NHTSA and IIHS may vary, the CLS-Class typically performs well in crash tests due to its robust construction and advanced safety technologies. Euro NCAP ratings are typically high as well.

Optional features include a Burmester surround sound system, massaging front seats, a head-up display, and an augmented reality navigation system, further enhancing the luxury and convenience of the CLS-Class.

What Colors Options are Available?

Exterior Colors
Black
Obsidian Black Metallic
Polar White
Selenite Grey Metallic
Mojave Silver Metallic
Lunar Blue Metallic
designo Diamond White Metallic
designo Selenite Grey Magno
Graphite Grey Metallic
Rubellite Red Metallic
Emerald Green Metallic
Tierra Brown Metallic
Interior Colors
Neva Grey/Magma Grey
Black/Black
Black/Espresso Brown
Macchiato Beige/Magma Grey
designo Classic Red/Black
designo Saddle Brown/Black
designo Platinum White Pearl/Black
Yacht Blue/Black

2021 Mercedes-Benz CLS-Class Prices and Market Value

When new, the 2021 Mercedes-Benz CLS-Class started at around $70,000 and could reach upwards of $85,000 with options. As of late 2023, used market prices generally range from $50,000 to $65,000, depending on mileage, condition, and trim level. Depreciation is moderate for the CLS-Class, reflecting its luxury status and desirability. Factors affecting resale value include mileage, condition, maintenance history, and the presence of desirable options such as the Burmester sound system or advanced driver-assistance features. Models with clean accident records and complete service histories command higher resale values.

2021 Mercedes-Benz CLS-Class Cost of Ownership

The 2021 Mercedes-Benz CLS-Class is a costly vehicle to own long-term. Insurance premiums are higher due to its luxury status and repair costs. Fuel costs are moderate, depending on driving habits, but premium fuel is required. Maintenance and repair costs are significantly higher than average due to the complexity of the vehicle and the price of genuine Mercedes-Benz parts. Expect to spend a considerable amount on scheduled maintenance and potential repairs over the lifespan of the vehicle.

2021 Mercedes-Benz CLS-Class Fuel Efficiency

Fuel Type Gasoline Hybrid
Fuel Capacity -
City Mileage -
Highway Mileage -

2021 Mercedes-Benz CLS-Class Safety Rating

NHTSA
Overall Rating Not Tested
Overall Frontal Star Rating Not Tested
Side Overall Star Rating Not Tested
Overall Rollover Star Rating Not Tested
Combined Front Seat Rating Not Tested
Combined Rear Seat Rating Not Tested
Overall Frontal Star Rating Not Tested
Frontal Barrier Star Ratings Not Tested
Overall Side Star Rating Not Tested
Side Barrier Star Ratings Not Tested
Side Pole Star Rating Not Tested
Combined Side Barrier And Side Pole Star Ratings Not Tested
Rollover Resistance Star Rating Not Tested

2021 Mercedes-Benz CLS-Class Insurance

Insurance for a 2021 Mercedes-Benz CLS-Class is moderately priced, reflecting its status as a Coupe with strong safety ratings and
reasonable repair costs.

How Does the 2021 Mercedes-Benz CLS-Class Compare to Other Coupe?

The 2021 Mercedes-Benz CLS-Class competes with vehicles like the Audi A7, BMW 8 Series Gran Coupe, and Porsche Panamera. In terms of performance, the CLS-Class offers comparable engine options to the A7 and 8 Series Gran Coupe, though the Panamera offers higher-performance variants. Feature-wise, the CLS-Class boasts a luxurious interior and advanced technology, similar to its rivals. However, reliability can be a concern, with some competitors, especially the Lexus GS (though discontinued after 2020) often scoring higher in reliability surveys.

Price-wise, the CLS-Class is generally in line with the A7 and 8 Series Gran Coupe. The Panamera tends to be more expensive, especially when equipped with options.

Alternatives to consider include:
  • Audi A7: Offers a similar blend of style and practicality with a more user-friendly infotainment system and potentially better reliability.
  • BMW 8 Series Gran Coupe: Provides a sportier driving experience and a wider range of engine options.
  • Porsche Panamera: Delivers superior performance and handling but at a higher price point.

Choosing between these vehicles depends on individual priorities. If styling and luxury are paramount, the CLS-Class is a strong contender. If reliability is a major concern, the A7 or considering a pre-2021 Lexus GS may be better choices. For ultimate performance, the Panamera is the clear winner.

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Final Verdict: Is the 2021 Mercedes-Benz CLS-Class a Good Coupe?

The 2021 Mercedes-Benz CLS-Class is ideal for buyers seeking a stylish and luxurious sedan with coupe-like aesthetics. It's a good choice for those who appreciate design and are willing to pay for the Mercedes-Benz brand experience. Whether it's worth buying depends on individual priorities and budget. A used model can offer significant savings, but a thorough pre-purchase inspection is crucial. Consider models with lower mileage and a comprehensive service history. The CLS 450 trim offers a good balance of performance and features. If performance is a top priority, the AMG CLS 53 is a compelling but more expensive option. Ultimately, the CLS-Class is a desirable vehicle for those who value style and luxury, but buyers should be aware of the potential ownership costs and reliability concerns.

2021 Mercedes-Benz CLS-Class Owner Reviews

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Drew B

Drew is a seasoned automotive expert and contributor to VinCheck.info. With nearly 15 years of experience as a former Porsche technician, he brings a wealth of hands-on knowledge to his writing. Born in North Carolina, a region renowned for its deep-rooted NASCAR culture, Drew developed a passion for cars early in life, often building and working on vehicles from a young age. At VINCheck, Drew leverages his extensive technical background to provide in-depth analyses of various vehicles. His articles often focus on engine performance, reliability, and maintenance insights, offering readers practical information grounded in real-world experience. Some of his notable contributions include reviews on the Mazda CX-5's longevity and detailed examinations of engine options for models like the 2011 Toyota Camry and Tacoma